Tramadol information

1. What is Tramadol and what is used?

Tramadol is a medicine belonging to the group of natural alkaloids of opium and other opioid, tramadolum. Analgesic effect occurs rapidly and persists for several hours.
Tramadol is packed in boxes containing 2 blisters Al / PVC of 10 capsules.
One capsule contains 50 mg of tramadol hydrochloride and excipients: microcrystalline cellulose, sodium starch glycol, talc, magnesium stearate.
Body of capsule: titanium dioxide (E 171), p-hydroxybenzoate methyl p-hydroxybenzoate propyl, gelatin.
The capsule: titanium dioxide (E 171), Patent blue V (E 131), Brilliant black (E 151), azorubin (E 122), Ponca 4 R (E 124), p-hydroxybenzoate methyl p-hydroxybenzoate propyl, gelatin.

That is used for Tramadol?
Tramadol is a medicine used to treat acute or chronic pain of moderate intensity to severe, for example: post-traumatic pain (wounds, fractures), severe neuralgia, cancer pain, myocardial infarction or associated diagnostic or therapeutic interventions.
2. Before using Tramadol

Tell your doctor if you dumenavoastră chronic diseases, metabolic disorders, hypertension, hypersensitivity, or taking other medicines.

You should not use Tramadol?
You should not use Tramadol if you have a hypersensitivity to tramadol hydrochloride or any excipient of the product, or perform treatment with inhibitors monoaminooxidazei (IMAO).
The product should not be used in children younger than 1 year.
The product should not be administered to patients with acute ethanol intoxication, hypnotics, analgesics or other drugs acting on central nervous system.

Warnings and precautions:
Tell your doctor if:

* You hypersensitivity to opioid analgesics,
*'re Prone to the addiction (etilism, addictive drugs or drugs)
* You have occasional seizures etiology brain (epileptic)
* Have kidney problems (if necessary, your doctor will increase the interval between doses, at least at the start of treatment)
* Have liver problems (if necessary, your doctor will reduce the dose or increase interval between doses),
* You have or have had brain trauma,
* You have severe breathing problems.

Use Tramadol with ingestion of foods and liquids
Patients should not consume beverages containing ethanol during treatment with tramadol.

Task
Before using any product, ask your doctor or pharmacist dumenavoastră.
The safety profile of using the product during pregnancy has not been investigated. High doses may have harmful effects on the fetus and new-born.

Lactation
Before using any product, ask your doctor or pharmacist dumenavoastră.
Bear in mind that, during lactation, about 0.1% of the amount of medicine is excreted in breast milk. Usually, not breast-feeding should be discontinued if it was used a dose of tramadol.

Effects on ability to drive and use machines
Drug affects the ability to drive or use machines, especially if it is associated with the consumption of beverages containing ethanol.

What medications interact with Tramadol?
Dumenavoastră Tell your doctor or pharmacist if you are using or have recently used other drugs even if they are of those that can be obtained without prescription.
The tramadol may be potentiated by co-administration of drugs acting on the central nervous system (anesthetic, antidepressants, antipsychotics, sedatives, hypnotics) or consumption of beverages containing ethanol.
Tramadol should not be used in combination with IMAO.
Administration of tramadol carbamazepină increasing metabolism, and therefore needed higher doses of tramadol.
Use of selective inhibitors of the serotonin recaptării, triciclice and neuroleptice antidepressants may increase the risk of seizures.

Important information concerning the excipients
Colors azorubin (E 122), Ponca 4 R (E 124) and Brilliant black (E 151) can cause allergic-type reactions including anaphylactic and bronhospasm patients susceptible, especially those with a history of asthma and allergy.
3. How to use Tramadol?

Follow strictly the doctor. Recommended doses should not be changed and the treatment should not be stopped without first discussing with your doctor.
Ask your doctor about treatment duration.
Doses vary depending on the patient. Number of doses, interval between administration and duration of treatment depend on the type and severity of pain and sensitivity of individual patients.
For adults and children over 14 years, the recommended dose is 50 mg tramadol hydrochloride (Tramadol 1 capsule). Capsule should be administered with a sufficient amount of liquid. If therapeutic response is not satisfactory, it can still be given a dose range similar to the 30-60 minutes.
Doses may be administered to inteval 4-6 hours.
Adult daily dose administered must not exceed 400 mg of tramadol hydrochloride (Tramadol 8 capsules).
In patients with renal or hepatic preciosity recommended the use of smaller doses at intervals of time greater.
In patients aged over 75 years, the daily dose administered must not exceed 300 mg of tramadol hydrochloride (Tramadol 6 capsules).
Tramadol should not be used for a period of time than is absolutely necessary.
Treatment with long tramadol be monitored carefully.

If you think that the effect of Tramadol is too strong or too weak, contact your doctor or pharmacist.

If you used more than Tramadol should have:
If you take more capsules than you have been prescribed, contact your doctor immediately dumenavoastră or pharmacist.
If by mistake you use a double dose of Tramadol, will not show significant side effects. If the administered dose is substantially higher than recommended, there may be signs of intoxication following: disturbance of consciousness, seizures, hypotension, tachycardia, mydriasis mioză or, problems with breathing.
In case of severe intoxication, with loss of consciousness and superficial breaths, naloxone should be administered, and in case of producing seizures diazepam intravenously.

If you forget to use Tramadol:
Do not use a double dose to compensate a skipped dose.
Use the next dose at the appointed time.

What are the risks in case of disruption of Tramadol?
Abrupt discontinuation of treatment may sometimes cause prolonged symptoms of withdrawal, so the decision to discontinue treatment should be medical dumenavoastră.
4. Possible side effects

Like all medicines, Tramadol may cause side effects.
Adverse reactions are most often associated with administering large doses of medication. May occur transpiraţii, vertigo, nausea, dizziness, dryness of mouth and tiredness. Rare side effects include tachycardia, hypertension, hypotension.
Sometimes it may appear headache, vomiting, constipation, gastrointestinal problems (abdominal distention, abdominal flatulence).
There are very rare reports of motility disorders, the disorder of appetite and urination (retention of urine, frequent urination).
Signs of stimulation of the central nervous system may occur in exceptional circumstances and include the changes (euphoria, emotional lability, anxiety), changes of activity (stimulation or inhibition of activity), disorders of perception and hallucinations.
Were observed allergic skin reactions (pruritus, rash). Can not be completely excluded any allergic reactions causing shock.
If you experience some side effects, were not mentioned in this leaflet, please ask your doctor or pharmacist.
5. How should hold Tramadol?

Do not use after the expiry date shown on the packaging.
A store below 25 ° C in the original packaging.
Keep out of reach of children.

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